Marta Gawin

DeisoLAB - isotopic envelope identification by analysis of the spatial distribution of peptides in MALDI-MSI data

A new approach (DeisoLAB) is introduced to handle extensive peptide data obtained in mass spectrometry imaging experiments and detect potential isotopic envelopes. It is based on a combination of a fuzzy-inference system and analysis of spatial distribution of peptides. Potential...

Inflammasome Inhibitor MCC950 Attenuates Methamphetamine-Induced Hippocampal Neurotoxicity and Aberrant Neurogenesis in a Sex-Dependent Manner

Methamphetamine (METH) is a known proinflammatory agent; however, the impacts of inflammasomes on its neurotoxic effects are not fully understood. In the present study, we assessed the impact of prolonged METH administration on the hippocampal inflammasome profile in male and fem...