Marta C Alonso-Moreno

Regional differences in dendritic spine morphology and innervation of the trisynaptic circuit of a mouse model of GSK-3β overexpression

Abstract The trisynaptic circuit, which includes the entorhinal cortex (EC), dentate gyrus (DG), and Cornu Ammonis (CA1, CA2, and CA3) of the hippocampus, is among the regions first affected by Alzheimer’s disease (AD). Glycogen synthase kinase-3β (GSK-3β) has emerged as a key en...