Mark T. Hamann

Phenolic Metabolites as Therapeutics for Chronic Diseases: One Researcher’s PAINS Is Another’s Translatable Polypharmacology

Abstract Phenols, natural and semisynthetic compounds in which a hydroxylated or oxygenated aromatic scaffold is a defining structural feature, occupy a paradoxical position in drug discovery. On the one hand, these compounds are frequently scrutinized for triggering Pan-Assay IN...