Mark J. Jaroszeski

Intratumor delivery of a novel plasmid combination induces high levels of metastatic melanoma regression

Direct intratumoral administration of immune-stimulating agents can generate systemic immunity following a tumor-localized immune response. Interleukin 12 (IL-12) activates T cells and reverses immunosuppression, generating a localized patient-antigen-specific immune response. Ch...