Margarita Martí-Nicolovius

Sex-specific cognitive and metabolic effects of lifelong caloric restriction and sodium butyrate administration in aging rats

Aging is associated with progressive metabolic dysfunction and cognitive decline, which is often accompanied by hippocampal dysfunction and sex-specific vulnerabilities. Caloric restriction (CR) and sodium butyrate (NaBu), a short-chain fatty acid that acts as a histone deacetyla...