Marcos Aurélio Carpina de Oliveira Filho

Molecular insights and ADMET profiling of iridoids as candidate leads for erectile dysfunction therapy

Abstract Context Erectile dysfunction (ED) significantly affects male psychosocial health and has an increasing incidence. Although phosphodiesterase 5 (PDEi-5) inhibitors are the first-line therapy, the occurrence of visual side effects resulting from cross-inhibition of the PDE...