Marco D’Abramo

Synergistic π–π Stacking and Hydrogen Bonding of Doxorubicin Electrostatically Bound to Sodium Alginate Drive the Formation of Supramolecular Nanoparticles with Exceptional Drug Loading

Doxorubicin hydrochloride (DX) is a widely used chemotherapeutic agent whose severe side effects can be attenuated by suitably designing drug delivery systems. The complexation between DX and the biocompatible and biodegradable sodium alginate (ALG) results in the formation of DX...