Marc Hainaut

Pharmacokinetic Modeling and Dosing Simulations of Temocillin in Children With Urinary Tract Infections

Background: Temocillin, active against most extended-spectrum β-lactamases (ESBL)-producing Enterobacterales , is increasingly considered a carbapenem-sparing option for Gram-negative infections. Despite a recommended pediatric dose of 25–50 mg/kg/d in 2 administrations, its phar...