Manuel Haschke

Angiotensin peptide and aldosterone concentrations in response to four classes of blood‐pressure-lowering drugs in hypertensive patients: A randomized trial

Abstract The renin angiotensin aldosterone system (RAS) regulates blood pressure and fluid balance by a cascade of angiotensin (Ang) peptides. Antihypertensive drug classes differentially modulate this cascade. This study examined how four mechanistically distinct antihypertensiv...

Deprescribing of proton pump inhibitors in internal medicine in-patients: A retrospective observational study.

Background Proton pump inhibitors (PPI) treat gastrointestinal disorders and are often overprescribed or continued unnecessarily, despite potential long-term adverse effects (e.g. infections). Deprescribing is recommended when indications are unclear or treatment unnecessarily pr...