Manuel Fuentes-Mateos

Isoform-Specific Modulation of PI3K/Akt1 Signaling by Orai Channels in Estrogen Receptor-Positive Breast Cancer

The phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is a fundamental intracellular axis that integrates extracellular stimuli to orchestrate essential cellular processes. The activation of Akt1 represents a key determinant of aggressiveness in estrogen receptor positive (E...