Manju Devi

Asymmetric Access to Spirobenzofuran Oxindoles via Organocascade Reaction of Unprotected 3-Chlorooxindoles with 2-Hydroxy-β-Nitrostyrenes

Abstract A highly enantioselective methodology has been developed to access oxindole-fused spiro dihydrobenzofuran, applicable to a protecting-group-free reactant, with high bond efficiency (1 new C–C and 1 C–O bond) and two contiguous stereocenters. Gram-scale and stereodivergen...