Manfred Grabherr

K-MARVEL: K-Mer-based antimicrobial resistance virtual exploration lab

Abstract The rapid global spread of antimicrobial resistance (AMR) necessitates a new generation of computational tools for its surveillance. While next-generation sequencing offers unprecedented insight into the resistome, current methods face a trade-off: assembly-based approac...

Voyager: rapid taxonomic characterization of long-read mixed-species sequencing samples in sorted motif distance space

Abstract Voyager is a novel algorithm that complements real-time sequencing by rapidly mapping long sequencing reads with insertion and deletion errors to a known database of organisms. It utilizes Sorted Motif Distance Space , distances between exact matches of short motifs sort...