Manabu Muto

P1.094. Cooporation of Aldh2 Deficiency and Tp53 Loss in Alcohol-Mediated Esophageal Squamous Field Cancerization

Abstract Topic Esophageal Cancer: Esophageal Carcinogenesis Background Field cancerization in the upper aerodigestive tract is driven by alcohol, ALDH2 polymorphism, and TP53 mutation. However, animal models reflecting these factors are lacking. This study aims to clarify the com...