Mallikharjuna Rao Lambu

An ″α-Methylsulfone″ Transfer Agent: Synthesis and Application of γ-Ketosulfones

Abstract An operationally simple, metal-free one-pot method for the synthesis of γ-ketosulfone from ketone has been developed using aryl/alkyl sulfonyl hydrazide-formaldehyde as an ″α-methylsulfone″ transfer agent. This one-carbon elongation method, promoted by a TFA-morpholine s...