Mallikarjuna Reddy Kesama

Programmable Assembly of Higher‐Order DNA Nanostructures from Microbial ssDNA Staple Libraries

Bottom-up manufacturing of structural DNA nanotechnology requires a long single-stranded DNA (ssDNA) scaffold and hundreds of short (∼30 nt) ssDNA staples. However, large-scale production is limited by the high cost and environmental impact of solid-phase chemical staple synthesi...