Malkeet Singh

Mechanochemical Access to 2,4-Diaroyl-5-aminothiazoles from β-Ketothioamides at Room Temperature

Abstract A mechanochemical approach to hitherto unreported 2,4-diaroyl-5-aminothiazoles via formal [3 + 2] heteroannulation of β-ketothioamides with 3-(hydroxyimino) chromane-2,4-diones has been developed utilizing SiO2-assisted hand grinding in a mortar with pestle at room tempe...