Mahmoud E. S. Soliman

Multi-target drug discovery of Sclerocarya birrea bioactive moieties against drug resistance in triple-negative breast cancer (TNBC) targeting BCL2, CASP3, and JUN modulation; a polypharmacological and molecular modelling approach

Abstract Triple-negative breast cancer (TNBC) remains one of the most aggressive breast cancer subtypes, characterized by poor prognosis and limited therapeutic options due to drug resistance. In this study, a network pharmacology-based multi-target drug discovery approach was ap...