Maha Ameur

Synthesis, design and integrated in vitro/in silico assessment of novel cyano-amide derivatives

A novel and an efficient synthesis of a series of cyano-amide derivatives 3a-h was achieved via solvent-free reaction of benzylcyanide derivatives 1 with isocyanate derivatives 2 at room temperature. The produced components were structurally characterized by NMR spectroscopy mult...