Magdi E. A. Zaki

A Topological and Spatial Analysis of FDA‐Approved Drugs, Blood‐Brain Barrier Permeants, Natural Products, and Metabolites

In this study, we present a comprehensive structural analysis of four distinct chemical libraries: FDA‐approved drugs, blood‐brain barrier (BBB) permeable agents, natural products (UNPDA), and human metabolites. Our multidimensional profiling reveals fundamental divergences in mo...

Quality by Design‐Guided Transethosomal Gel of Donepezil Hydrochloride and Quercetin for Potential Alzheimer's Management: Stability‐Indicating Eco‐Compatible RP‐HPLC Method

ABSTRACT Alzheimer's disease requires innovative therapeutic strategies that not only alleviate symptoms but also protect neurons. Donepezil hydrochloride, a cholinesterase inhibitor, and quercetin, a potent antioxidant, were co‐formulated into a transethosomal gel to enhance bra...

Arsenic removal from wastewater using the bio-based graphene oxide and magnetite nanocomposites: reaction kinetic study

Water contamination with arsenic (As) is a global issue challenging the environment, ecosystem, and human health. Among arsenic decontamination techniques, sorption is highly acknowledged, efficienct, low cost and simple technique and gaining much interest in recent decades. Effi...