Magdalena Blei

The Second Nitrogen Fits: Development of Diazine-Based Macrocyclic Chelators to Stably Bind Radionuclides Used in Targeted Alpha Therapy

Abstract Identifying suitable chelators for 212Pb, 223Ra, and 225Ac and their diagnostic counterparts 131Ba, 133La, and 203Pb remains one of the major challenges in the development of radiopharmaceuticals for targeted alpha therapy. Four novel macrocyclic chelators containing the...