Magali Cucchiarini

Proteomic landscape of IGF-I gene transfer in osteoarthritis-derived human bone marrow stromal cells undergoing chondrogenesis

Abstract Background Osteoarthritis (OA) is a progressive joint disease marked by the breakdown of cartilage and impaired repair capacity. Gene therapy applied to human bone marrow-derived adherent stromal cells (BM-MSCs) with recombinant adeno-associated virus (rAAV) vectors repr...