Madeline B. Ho

EPR and ENDOR Characterization of Fe- and S-Ethylated [4Fe-4S]1+ Clusters, and a Cascade of H-Atom Abstractions Following Photolysis of the Fe–C Bond

Abstract Initiation of radical reactions by radical S-adenosyl-l-methionine (SAM) enzymes involves a central organometallic intermediate denoted Ω, with an Fe–C bond between the unique iron of a [4Fe-4S]3+ cluster and 5′C of 5′-dAdo. In some radical SAM (RS) enzyme processes, the...