Madeleine M. Allen

HIV-1 hijacks HGF/c-MET signaling to promote viral entry and replication in primary CD4 + T cells

ABSTRACT The mesenchymal-epithelial transition factor (c-MET) is a receptor tyrosine kinase best known for mediating hepatocyte growth factor (HGF) signaling in cancer, but its role in HIV-1 infection has remained unclear. Here, we identify c-MET as a host factor that promotes HI...