M Kikuchi

Urinary C5a as a Noninvasive Marker of Renal Activity, Histopathological Severity, and Outcomes in ANCA-Associated Vasculitis

Background: Complement activation plays a central role in the pathogenesis of ANCA-associated vasculitis (AAV). However, the clinical implications of urinary complement fragments remain unclear. We investigated whether urinary complement fragments reflect the severity of renal in...