M. B. Hoare

A live‐cell autophagy reporter reveals reversible vacuolation in naked mole‐rat skin fibroblasts under lysosomal stress

Abstract Naked mole-rats (NMRs, Heterocephalus glaber ) display unusual longevity and resistance to age-related decline, and accumulating evidence suggests that their autophagy–lysosome pathway (ALP) is regulated differently from that of conventional mammalian models. However, mo...