Lyndsey M. Kirk

Synaptopodin KO rat for assessing the dendritic spine apparatus and axonal cisternal organelle in synaptic plasticity, development, and behavior

Abstract The actin-binding protein synaptopodin (Synpo) regulates the cytoskeleton and organization of endoplasmic reticulum, thereby amplifying intracellular Ca 2+ signaling. Knockout (KO) mouse models have been used to study the role of Synpo in kidney and brain functions, wher...