Luzheng Zhang

Single-cell transcriptomics landscape decodes cardiac fibroblast heterogeneity and reveals PDK4-driven profibrotic activation during cardiac fibrosis

Cardiac fibroblasts act as a key driver of myocardial fibrosis across various heart diseases, but the recently recognized heterogeneity within fibroblast populations has hindered mechanistic understanding. This study aimed to investigate the heterogeneity of cardiac fibroblasts a...