Luxi Wu

Identification of key signature genes and construction of a diagnostic model for heart failure based on integrative transcriptomic and eQTL-based analyses and single‑cell eQTL Mendelian randomization

Heart failure (HF) is a life-threatening end-stage syndrome of cardiovascular disease with a rapidly increasing global incidence. Its underlying biological mechanisms remain unclear, and current biomarkers lack sufficient diagnostic accuracy. Single-cell eQTLs and Mendelian rando...