Luke J Mitchell

Systemically delivered Bacteroides thetaiotaomicron -derived bacterial extracellular vesicles inhibit primary and metastatic melanoma growth

ABSTRACT The gut microbiome can contribute to anti-tumor immunity and cancer therapy responses, but translating live microbe-based interventions remains challenging due to safety, controllability, and delivery constraints. Bacterial extracellular vesicles (BEVs) are an attractive...