Luiz Guidi

Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep.

One of the most distinctive features of the mammalian cerebral cortex is its laminar structure. Of all cortical layers, layer 6b (L6b) is by far the least studied, despite exhibiting direct sensitivity to orexin and having widespread connectivity, suggesting an important role in...