Luitgard Nagel‐Steger

Structural and functional insights into the p160 Rho-associated coiled-coil-containing protein kinase ROCK

Abstract Rho-associated protein kinases (ROCK1/2) are critical regulators of fundamental cellular processes and represent promising therapeutic targets for various pathologies, particularly cardiovascular disease. While the terminal globular kinase domain and the PH-C1 tandem (PH...