Luisa Solimando

The efficacy and safety of celecoxib for postoperative pain in major orthopedic surgery: a systematic review and pairwise meta-analysis

Effective postoperative pain management is crucial for surgical recovery, yet opioid-based therapies carry significant risks of addiction and adverse effects. Celecoxib, a selective COX-2 inhibitor, has emerged as a promising non-opioid alternative within multimodal analgesic pro...