Luigi Nibali

Antimicrobial Resistance in Periodontal Disease: Rethinking Adjunctive Therapy in the Metagenomics Era, the Pressing Need for Precision Treatment and Periodontal Resistome Mapping

ABSTRACT Systemic antibiotics are effective when used as adjunctive therapy in the treatment of periodontitis; however, their use must be balanced against antimicrobial resistance, which is a major threat to global public health. This review provides an expert synthesis of the li...

Accuracy of transfer learning in predicting peri-implantitis onset from intraoral radiograph: A multi-center longitudinal retrospective study

BACKGROUND: The growing application of artificial intelligence in dentistry has opened new opportunities for predicting peri-implantitis (PI) using convolutional neural networks (CNNs). Transfer learning, where knowledge from a model pre-trained on a large dataset is adapted to a...

Interdental brushing behaviour in adults: Influence of periodontal status and socioeconomic factors

Abstract Aim To evaluate patterns of interdental brush (IB) use across different stages and grades of periodontitis and to examine associations with socioeconomic, demographic, and behavioural factors. Methods This cross-sectional study included 375 adults referred for secondary...

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

ABSTRACT Aim Drug‐target Mendelian randomisation (MR) studies investigate whether genetically proxied modulation of druggable proteins affects the risk of periodontitis, thereby identifying potential pharmacological targets. Methods A systematic review was conducted following PRI...