Lucio Frydman

Heteronuclear polarization transfers between spin-locked and anti-longitudinal spin states in the NMR of liquids and spinning solids

Recently, a three-spin rotating-frame nuclear magnetic resonance (NMR) analog of the cross effect, whereby polarization was transferred between two 13Cs and an 15N in a single crystal, was reported. This effect is closely related to the mixed rotational and rotary resonance (MIRR...

High–spatiotemporal resolution deuterium metabolic imaging enables in vivo phenotyping of intra- and intertumoral heterogeneity

Intra- and intertumoral heterogeneities raise fundamental biological questions and have important implications for accurate cancer diagnosis, prognosis, and treatment. These heterogeneities reflect tumor complexity, including a pronounced diversity in metabolic phenotypes and pro...