Luca Pagliaroli

Bepirovirsen induces innate immune proteins independent of HBV

BACKGROUND: Bepirovirsen, an antisense oligonucleotide that targets all hepatitis B virus (HBV) mRNAs, is in development for the treatment of chronic HBV infection. Clinical studies have demonstrated that bepirovirsen has multiple mechanisms of action, including lowering HBV DNA,...