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Yes-associated Protein Is Involved in Tubular Epithelial Cell Apoptosis and Renal Tissue Damage in Early Sepsis-Associated Acute Kidney Injury

Abstract Sepsis-associated acute kidney injury (SA-AKI) is a distinct form of acute kidney injury in critically ill patients. It is characterized by tubular epithelial cell damage and apoptosis. The Hippo-Yes-associated protein (YAP) pathway plays dual roles in renal injury and r...