Lorenzo Gramolini

Ga3+ Replacing of Fe3+ as a “Trojan Horse” Antimicrobial Strategy: Modeling the Process within Bacterial Catalase–Peroxidase KatG

Abstract Replacement of Fe3+ by Ga3+ has emerged as a promising “Trojan horse” antimicrobial strategy in response to the growing threat of antibiotic-resistant bacteria. Because many bacterial proteins hijack host iron to sustain essential redox processes, substitution with redox...

Tunable Osmium Complexes as pH-Insensitive Redox Reportersfor Electrochemical Biosensing

Abstract The lack of robust and tunable redox reporters continues to hinder the development of high-performance electrochemical biosensors. In this work, we present a combined computational and experimental investigation of a family of water-compatible Os(II) complexes as pH-inse...