Loïc Yengo

Within-family effect of ancestry on complex traits in a Mexican population

Abstract Human populations differ in disease prevalence and phenotypes, but the extent to which differences are caused by genetic factors is unknown for most complex traits. Comparing phenotypic means across populations is confounded by environmental differences and using polygen...

Multi-ancestry conditional and joint analysis applied to GWAS summary statistics

Manc-COJO (Multi-Ancestry Conditional and Joint Analysis) is a C++ software package for identifying independent association signals from multi-ancestry GWAS summary statistics. By jointly modelling association signals across ancestry groups while accounting for ancestry-specific...