Lisbeth Verk

ADAR1 is increased in prostate cancer progression and silencing reduces A-to-I editing and cell growth while enhancing apoptosis and adhesion

Abstract Adenosine deaminase acting on RNA 1 (ADAR1) catalyses adenosine-to-inosine (A-to-I) RNA editing and has emerged as a regulator of cell biology. Here, we investigate the expression and function of ADAR1 in prostate cancer using in vitro models and clinical patient cohorts...