Lingzhou Zhao

Evaluation of 68Ga Labeling Strategies and Thermostability of HER2-Targeted Nanobody NB46

Abstract The HER2-targeted nanobody NB46 was evaluated for labeling strategy flexibility and thermostability. Random and site-specific 68Ga labeling strategies were compared. Both conjugates exhibited high HER2 affinity, comparable to unmodified NB46. Cellular uptake, pharmacokin...