Ling Yan Zhang

Multi-omics characterization of P2RX4-associated immune microenvironment features and proof-of-concept observations of peritumoral radiomic phenotypes in TNBC

Abstract Background Triple-negative breast cancer (TNBC) is characterized by a highly heterogeneous and immunosuppressive tumor microenvironment (TME). While the ATP-gated receptor P2RX4 is associated with inflammation, its cell-specific expression patterns, associations with TME...