Liang Yu

Proteoform-Resolved Interaction Mapping of Target Protein Complexes in Living Cells via Tracelessly Releasable Cross-Linking

Abstract Proteoform-resolved interaction analysis is critical for understanding the functional diversity of multiple proteoforms from the same gene and their complexes. However, current technologies are still limited in resolving in vivo interactions at the proteoform level. In v...

Serum neutrophil elastase as a potential non-invasive biomarker for assessing hepatic fibrosis in chronic hepatitis B patients

The role of neutrophil elastase (NE) in liver fibrosis caused by chronic hepatitis B (CHB) has not been fully clarified. This study sought to measure serum NE concentrations in individuals with CHB and to determine whether NE could serve as a noninvasive indicator for assessing C...

A Ship Yaw-Angle Separation Method Based on Empirical Mode Decomposition and Multi-Dimensional Physical–Statistical Evaluation

The yaw-angle signal output by shipboard attitude sensors (e.g., inertial navigation systems) is a composite of the heading and wave-induced yaw (WIY). The heading reflects large-scale directional changes due to maneuvering or voyage planning, exhibiting slowly varying, trend-lik...