Li Ming Huang

A "Probability Stratification and Staged Clearance" Strategy for HIV Cure ——A Systematic Protocol Based on Functional Separation Editing of Hematopoietic Stem Cells, Active Latent Reservoir Reduction, and Patient Stratification

Abstract:The fundamental barrier to an HIV cure is not a lack of technical methods, but theprobabilistic nature of viral escape. As long as a single latently infected cell capableof utilizing the CXCR4 co-receptor (X4-tropic) remains in the body, any strategy thatonly blocks the...

A "Probability Stratification and Staged Clearance" Strategy for HIV Cure ——A Systematic Protocol Based on Functional Separation Editing of Hematopoietic Stem Cells, Active Latent Reservoir Reduction, and Patient Stratification

Abstract:The fundamental barrier to an HIV cure is not a lack of technical methods, but theprobabilistic nature of viral escape. As long as a single latently infected cell capableof utilizing the CXCR4 co-receptor (X4-tropic) remains in the body, any strategy thatonly blocks the...