Leyuan Wang

Nanoparticle‐Based Delivery Strategies for Targeted Protein Degradation

Targeted protein degradation (TPD) has fundamentally redefined pharmacological intervention, shifting from classical occupancy-driven inhibition to event-driven elimination of undruggable pathogenic proteins, holding great promise for treating various intractable diseases. Althou...

Clinical features and prognostic factors in paediatric medulloblastoma: a retrospective cohort study

To evaluate the clinical characteristics, outcomes, and prognostic factors associated with paediatric medulloblastoma (MB). We retrospectively analysed paediatric MB patients treated at Xiangya Hospital Central South University from January 2015 to July 2023. Overall survival (OS...