Leyan Zhao

A Multi‐complex Virtual Screening Approach Exploring Machine Learning to Identify Potential PI3Kγ Inhibitors

ABSTRACT Phosphoinositide 3‐kinase gamma (PI3Kγ) plays a crucial role in regulating cellular physiological activities. However, the development of selective PI3Kγ inhibitors has proven particularly challenging due to the high sequence homology among residues near the ATP‐binding...