Lev Levintov

Nonadditive Conformational Effects of tRNA Core Modifications

Abstract Post-transcriptional modifications are known to regulate the structure and function of tRNA molecules. Compared to modifications in the anticodon region, the mechanistic effects of modifications in the core region of tRNA remain poorly understood. Using all-atom molecula...

Conformational Dynamics of Phase-Separating Methacrylated Carbohydrates

Abstract Polysaccharide-based materials, particularly dextran (Dex) derivatives, have emerged as versatile platforms for biomedical and materials science applications primarily due to their tunable chemical functionality and intrinsic biocompatibility. Native Dex is a highly hydr...