Leonard Azamfirei

Systems Bioengineering of Septic Shock Metabolism: Citrulline, β-Hydroxybutyrate and Plasma Biomarker-Based Phenotyping

Background: Although advances in critical care have improved short-term outcomes, sepsis survivors continue to face substantial chronic morbidity and impaired long-term survival. Conventional threshold-based tools such as the Sequential Organ Failure Assessment (SOFA) and Modifie...

Smart Cardiac ICU: Digital Integration, Predictive Analytics, and Perioperative Inflammation

Contemporary intensive care is operating in an environment with high complexity cases, large volumes of information, and vast physiological, biological and therapeutical data, collected from laboratory results, investigations, therapies for organ support, collected from systems t...