Lena Jonasson

Lymph node contraction links sex-biased naive CD8+ T cell decline to compromised antigen recognition during middle age

Abstract The abundance of diverse naive CD8 + T cell clones is essential for broad protection against infection and cancer, but how sex and aging jointly shape this compartment remains poorly understood. Here, using mouse models with supporting human data, we uncover a sex-biased...

Health-related quality of life, psychological well-being and physical activity in patients with mild-to-moderate ascending aortic dilation - a cross-sectional case-control study

Abstract Aim To investigate health-related quality of life (HRQoL), psychological well-being and physical activity in patients with mild-to-moderate ascending aortic dilation. Background While ascending aortic dilation often require lifelong surveillance due to the increased risk...