Author
Lei Yu
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Recent research
- Materials & Energy
Iridium-Catalyzed Asymmetric Hydrogenation of Pyridazine Salts under Batch and Flow
Abstract Herein, we report an [Ir(COD)Cl]2/(R)-SunPhos-catalyzed asymmetric hydrogenation of pyridazine salts to construct chiral hexahydropyridazines. The reaction tolerates a wide range of substituents, delivering products in up to 97% yield with 97% ee under mild reaction cond...