Lei Shi

Photoelectrocatalytic bromolactonization with NaBr as the bromine source coupled with hydrogen evolution

We report a mild and efficient photoelectrochemical (PEC) synthetic strategy for the construction of isobenzofuranone skeletons via bromolactonization using NaBr as the bromine source. This transformation proceeds in the absence of exogenous oxidants and additional catalysts, del...

Adamantyl-BOX Ligand Enabling Stereoselective Synthesis of Axially Chiral Aldehydes Bearing Vicinal Stereogenic Centers

Abstract Biaryl frameworks combining axial and multiple central chiralities are highly valuable in synthesis and drug discovery. However, simultaneous construction of axial and vicinal central chiralities faces severe matching/mismatching limitations. Herein, we describe a dual p...